James Watson & Francis Crick: Discovery of the Double Helix and Beyond by David E. NewtonThe biography series, aimed at young adults, profiles important modern-era scientists. The volumes focus on the lives of those men and women who, in the 19th and 20th centuries, made the greatest contributions to scientific knowledge. Each book looks at a scientist - or group of scientists - whose work had a major impact on a particular field. In simple prose, free of technical jargon, each scientists achievements are discussed, including the scientific principles underlying his or her work. The human drama of scientific work, conveying the excitement and frustration of research, as well as the exhilaration and rewards of discovery, are also depicted.
The Discovery of the Structure of DNA
Discovery of the structure of DNA
In Watson b. The reasons for her exclusion have been debated and are still unclear. The molecule that is the basis for heredity, DNA, contains the patterns for constructing proteins in the body, including the various enzymes. A new understanding of heredity and hereditary disease was possible once it was determined that DNA consists of two chains twisted around each other, or double helixes, of alternating phosphate and sugar groups, and that the two chains are held together by hydrogen bonds between pairs of organic bases—adenine A with thymine T , and guanine G with cytosine C. She was born into a prominent London banking family, where all the children—girls and boys—were encouraged to develop their individual aptitudes. She resigned her research scholarship in just one year to contribute to the war effort at the British Coal Utilization Research Association. There she performed fundamental investigations on the properties of coal and graphite.
British Broadcasting Corporation Home. This was one of the most significant scientific discoveries of the 20th century. He changed from physics to biology and in began to work at Cambridge University. In an American student, James Watson, arrived at the unit and the two began to work together. He then moved to Cambridge University. Watson and Crick worked together on studying the structure of DNA deoxyribonucleic acid , the molecule that contains the hereditary information for cells. Crick and Watson used their findings in their own research.
This page has been archived and is no longer updated. In reality, this is not the case. Then, in the decades following Miescher's discovery, other scientists--notably, Phoebus Levene and Erwin Chargaff--carried out a series of research efforts that revealed additional details about the DNA molecule, including its primary chemical components and the ways in which they joined with one another. Without the scientific foundation provided by these pioneers, Watson and Crick may never have reached their groundbreaking conclusion of that the DNA molecule exists in the form of a three-dimensional double helix. Although few people realize it, was a landmark year in genetic research, because it was the year in which Swiss physiological chemist Friedrich Miescher first identified what he called "nuclein" inside the nuclei of human white blood cells. The term "nuclein" was later changed to " nucleic acid " and eventually to " deoxyribonucleic acid ," or "DNA. Miescher thus made arrangements for a local surgical clinic to send him used, pus-coated patient bandages; once he received the bandages, he planned to wash them, filter out the leukocytes, and extract and identify the various proteins within the white blood cells.
Franklin's images allowed James Watson and Francis Crick to create and Linus Pauling's discovery that the molecules of some proteins have.
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Watson and Crick describe structure of DNA Photo: Model of DNA molecule In the late nineteenth century, a German biochemist found the nucleic acids, long-chain polymers of nucleotides, were made up of sugar, phosphoric acid, and several nitrogen-containing bases. He even suggested DNA might actually be the gene. Most people at the time thought the gene would be protein, not nucleic acid, but by the late s, DNA was largely accepted as the genetic molecule. Scientists still needed to figure out this molecule's structure to be sure, and to understand how it worked. In , Linus Pauling discovered that many proteins take the shape of an alpha helix, spiraled like a spring coil.